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Development Facilities

Bridge Laboratories Biomedical Research Vivarium

Bridge Laboratories is a preclinical Contract Research Organization (CRO) that provides U.S.-level regulatory-compliant drug development services globally. Bridge is U.S.-owned and headquartered in Gaithersburg, Maryland, with lab facilities in both the U.S. and Beijing, China. Bridge is known for its extensive work in toxicology, including vaccines, developmental and reproductive toxicology (DART), and safety pharmacology.
RS&H was contracted to provide Bridge Laboratories with programming and planning services for their U.S. and China campuses. The Beijing campus is located in the Zhongguancun Life Science Park, a 615-acre development dedicated to research, mid-level testing, start-up incubation, and medical research and treatment. The existing campus houses an 84,000-square-foot research facility, which is the first Asian pre-clinical CRO with western-level design standards.

As an expansion to the existing campus, RS&H, along with China IPPR International Engineering Corp., programmed and designed a five-story, 136,000-gross-square-foot full-service vivarium with research laboratories for toxicology testing. The facility includes 107 animal holding rooms, cage wash, surgery rooms, procedure rooms, and necropsy labs. The facility is supported by a full-service shipping and receiving dock segregated for animal and non-animal handling. The facility is designed to be both AAALAC multispecies accredited and U.S.-level GLP compliant.

Related Services: Planning

Toxicology Testing Laboratory Campus

RS&H provided programming, master planning, architectural design, and phasing strategy services for the design and multiphased construction of a new 293,000-square-foot Toxicology Testing Laboratory Campus for an international contract research organization.

As the first phase of the research campus, this 293,000-square-foot facility houses a toxicology laboratory and full-service vivarium for small animals and non-human primates. The vivarium is supported by a full-cage wash and decontamination suite, gown and garb areas, surgery suites, and radiology suites. Laboratories include testing laboratories for dose formulations and analysis, analytical chemistry, bio-analytical high-throughput labs, immunochemistry, necropsy, histology, pathology, and clinical pathology.

Support functions include offices, conference facilities, a cafeteria, maintenance shops, and physical plant facilities. The facility is designed to accommodate efficiencies identified through a Six Sigma Process. Each area is developed based upon principles of process-driven analysis with the ability to expand each function as the facility's needs increase.

The full campus build-out supports a doubling of initial research capacity and includes a clinical research unit housing 75 volunteers for Phase I and II drug testing.

The campus site plan is carefully designed to allow the maximum functional efficiency with amenities, such as picnic and jogging areas within a secure campus boundary. Features include indigenous landscaping, retention areas, and separate visitor and staff entrances. Together, the campus provides a consistent corporate image of effective and efficient science in an innovative and stimulating campus environment.

Related Services: Architecture | Engineering | Laboratory Planning & Design